Plexin-b3
WebbBackground: Plexin B3. Plexin B3 is a type I transmembrane glycoprotein that belongs to the Plexin B subfamily of semaphorin receptors (1, 2). Human Plexin B3 contains a 44 amino acid (aa) signal sequence, a 1211 aa extracellular domain (ECD), a 21 aa transmembrane domain, and a 633 aa cytoplasmic domain that includes features … WebbHowever, the expression and role of plexin-B3 in hepatocellular carcinoma (HCC) is yet to be investigated. In the present study, plexin-B3 expression was measured in 14 paired …
Plexin-b3
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WebbPlexins are transmembrane protein receptors for semaphorin molecules. These molecules are involved in numerous cellular activities related to cell proliferation, adhesion along … WebbPlexin B3 is a type I transmembrane glycoprotein that belongs to the Plexin B subfamily of semaphorin receptors (1, 2). Human Plexin B3 contains a 44 amino acid (aa) signal …
Webb1 juli 2004 · Here we show that plexin-B3 is a high-affinity receptor specific for Sema5A. We further demonstrate that plexin-B3 activation by Sema5A mediates functional responses in plexin-B3-expressing cells (either fibroblasts, epithelial and primary endothelial cells). WebbGlycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells Glycoproteomics Identifies …
Webb25 aug. 2005 · We found evidence for plexin B3- and B2-dependent stimulation of neurite outgrowth, subtype-specific homophilic interaction of B3 and B2, respectively, and an … WebbPlexin-B3 interacts with c-Met through its sema domain and IPT domain.....86 Figure 14. ErbB-2 interacts with plexin-B3 through the sema domain and IPT domains.....89 Figure 15. Cloning strategy of pGEX-KG expression constructs encoding full-length plexin-B3 extracellular domain ...
Webb8 dec. 2024 · plexin-B3, plexin 6 GeneRIFs: Gene References Into Functions Data suggest that under physiological conditions Plexin-B3 is not essential for the development and function of the central nervous system. These results help to better comprehend mechanisms used for plexin B3 transcriptional regulation.
WebbPlexin-B3 (also plexin-6) is a 260-270 kDa member of the plexin-B subfamily, plexin family of proteins. It is found on postnatal neurons and oligodendroglia, and appears to have opposing functions. In a context-dependent manner, plexin-B3 may block cell process extension and induce growth cone collapse by binding to Sema5. cooling water condenser designWebb15 juli 2024 · In AD brains, virtually all cortical SPs were immunostained for plexin-B3, and plexin-B3 levels increased significantly in the Sarkosyl-soluble fractions. These findings … family safety monitor stopping websitesWebb19 dec. 2005 · Artigiani et al. (2004) showed that mammalian Plxnb3 is a high-affinity semaphorin-5A (SEMA5A; 609297) receptor. Plxnb3 was activated by Sema5a, and the … family safety ne marche pasWebbPlexin B3 (PLXNB3) is highly expressed in estrogen receptor-negative breast cancer, but the underlying mechanisms and consequences have not been thoroughly investigated. … family safety non funzionaWebb14 juli 2024 · These suggested that Plexin-A1 and Plexin-B3 all serve as the functional receptors for Semaphorin 5A in RA SFs. Moreover, given that Plexin-B3 expression did not differ significantly between... cooling water densityWebb29 mars 2024 · PLXNB3 plexin B3 Gene ID: 5365, updated on 29-Mar-2024 Gene type: protein coding Also known as: PLEXR; PLXN6; PLEXB3. See all available tests in GTR for … cooling water circulator zabdireso urces.comWebb11 apr. 2024 · The human Plexin B3 ECD shares 81%, 81%, 83% and 75% aa identity with mouse, rat, bovine and canine Plexin B3, respectively. It contains a sema domain and a PlexinSemaphorinIntegrin (PSI) or MetRelated Sequence (MRS) domain, each of which contains a potential proteolytic cleavage site (2). cooling water duty calculation