Phesgo monitoring

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August undefined, 2024

WebThe combination of trastuzumab and pertuzumab as an injection under your skin is called Phesgo. Having these drugs this way is quicker than having them into your bloodstream. You usually have these every 3 weeks. Your doctor will let you know if this is suitable for you and how many treatments you will have. WebMar 2, 2024 · Phesgo contains two active substances, pertuzumab and trastuzumab, which are already authorised for treating early and metastatic HER2-positive breast cancer and …

NDC 50242-260 Phesgo Label Information

WebPhesgo 600 mg/600 mg solution for injection Phesgo 1200 mg/600 mg solution for injection pertuzumab/trastuzumab. This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can help by reporting any side effects you may get. See the end of section 4 for how to report side effects. WebFollowing completion of PHESGO, continue to monitor for cardiomyopathy and assess LVEF measurements every 6 months for at least 2 years as a component of adjuvant therapy. … coding ide for chromebook

FDA approves combination of pertuzumab, trastuzumab, and …

WebPatients who receive anthracycline after stopping Phesgo may be at increased risk of cardiac dysfunction because of the long washout period of Phesgo; If possible, avoid … WebPhesgo offers faster administration of Perjeta and Herceptin under the skin in just minutes, compared to hours with standard IV administration. Phesgo can be administered by a healthcare professional in a treatment centre or at a patient’s home. WebJul 27, 2024 · The healthcare provider who gives you the Phesgo injection will closely monitor you for 30 minutes after your first dose. For later doses, you will be monitored for 15 minutes. Women who are pregnant or are planning to get pregnant should not be given Phesgo. Phesgo can cause embryo death and birth defects. coding implanted pump medication

Phesgo 1200 mg/600 mg solution for injection - medicines

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WebPHESGO is a prescription medicine approved for use in combination with docetaxel in adults who have HER2-positive breast cancer that has spread to different parts of the body … WebFollowing completion of PHESGO, continue to monitor for cardiomyopathy and assess LVEF measurements every 6 months for at least 2 years as a component of adjuvant therapy. PHESGO. In the FeDeriCa study, the percentage of patients with at least one cardiac disorder was 22% in the PHESGO arm. The most frequent cardiac adverse reaction in the ... caltex power steering fluidWebPHESGO ™ (pertuzumab, trastuzumab, and hyaluronidase-zzxf) is a prescription medicine approved for use in combination with chemotherapy for: use prior to surgery (neoadjuvant treatment) in adults with HER2-positive, locally advanced, inflammatory, or early stage breast cancer (tumor is greater than 2 cm in diameter or node-positive). caltex renovations inc

"WebNov 16, 2024 · Following completion of PHESGO, continue to monitor for cardiomyopathy and assess LVEF measurements every 6 months for at least 2 years as a component of adjuvant therapy. PHESGO. In the FeDeriCa study, the percentage of patients with at least one cardiac disorder was 22% in the PHESGO arm. The most frequent cardiac adverse … " - Phesgo monitoring

Phesgo monitoring

Pertuzumab/trastuzumab/hyaluronidase - Wikipedia

WebPhesgo® contains two separate monoclonal antibodies, trastuzumab and pertuzumab. Previously, trastuzumab and pertuzumab were used separately or in combination to … WebJun 29, 2024 · The recommended initial dose of PHESGO is 1,200 mg pertuzumab, 600 mg trastuzumab, and 30,000 units hyaluronidase administered subcutaneously over approximately 8 minutes, followed every 3 weeks ...

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WebPHESGO is a prescription medicine approved for use in combination with docetaxel in adults who have HER2-positive breast cancer that has spread to different parts of the body …

WebPHESGO administration can result in subclinical and clinical cardiac failure. The incidence and severity was highest in patients receiving PHESGO with anthracycline-containing … WebPHESGO administration can result in serious and fatal pulmonary toxicity. Discontinue PHESGO for anaphylaxis, angioedema, interstitial pneumonitis, or acute respiratory … Treatment regimens for early and metastatic breast cancer, based on … Printable Resources - Dosing & Administration PHESGO® (pertuzumab … Side Effects - Dosing & Administration PHESGO® (pertuzumab / trastuzumab ... PHESGO Access Solutions offers a range of access and reimbursement resources for … Trial Information - Dosing & Administration PHESGO® (pertuzumab / trastuzumab ...

WebData Monitoring: Yes ... Phesgo will be administered subcutaneously (SC) at a fixed non-weight-based dose. In the induction therapy phase, a loading dose (1200 milligram (mg) pertuzumab, 600 mg trastuzumab, and 30,000 units of recombinant human PH20 hyaluronidase [rHuPH20]) will be administered in the first cycle (1 cycle is 21 days). ... WebOct 13, 2024 · Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) is a combination of HER2 /neu receptor antagonists and an endoglycosidase indicated for use in combination with chemotherapy as neoadjuvant treatment of patients with HER2-positive, locally advanced, inflammatory, or early stage breast cancer (either greater than 2cm in diameter …

WebPHESGO is contraindicated in patients with known hypersensitivity to pertuzumab, or trastuzumab, or hyaluronidase, or to any of its excipients. Additional Important Safety Information Cardiomyopathy and Cardiac Monitoring • PHESGO administration can result in subclinical and clinical cardiac failure. The incidence and severity was

WebNov 16, 2024 · In patients receiving PHESGO for metastatic breast cancer with docetaxel, administer docetaxel after PHESGO. Observe patients for a minimum of 30 minutes after initial dose of PHESGO and 15 minutes after each maintenance dose of PHESGO for signs or hypersensitivity symptoms or administration-related reactions. coding in caviteWebMar 16, 2024 · The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. Last updated on emc: 16 Mar 2024 This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. View or print the patient leaflet as PDF caltex resources soldWebJun 29, 2024 · The prescribing information for phesgo includes a boxed warning to advise health care professionals and patients about the risk of potential heart failure, fetal harm, and lung toxicity. The FDA indicated that healthcare professionals should use similar monitoring parameters as those already used with IV pertuzumab and IV trastuzumab. … caltex resources calgaryWebJul 10, 2024 · For your initial dose, your healthcare professional will slowly inject Phesgo into your thigh over the course of eight minutes. They will monitor you for 30 minutes afterward for any reactions. Every three weeks, a maintenance dose of Phesgo will be injected over the course of five minutes. cal tex restaurants incWebOct 13, 2024 · PHESGO administration can result in serious and fatal pulmonary toxicity. Discontinue PHESGO for anaphylaxis, angioedema, interstitial pneumonitis, or acute … coding immediate postpartum hemorrhageWebNov 1, 2024 · Phesgo is indicated for use in combination with docetaxel for the treatment of adult patients with HER2-positive metastatic breast cancer who have not received prior … caltex refinery south africaWebThe nurses monitor you for about 4 to 6 hours afterwards to check for any reaction. If you have no problems, you can have further doses given over a shorter time. You will need … coding immunotherapy