WebApr 14, 2024 · The following mouse strains were used (all on a C57BL/6 background): Cdh5 CreERT2:ZsGreen l/s/l mice (control mice; TgCdh5-Cre/ERT2 1Rha) and Cdh5 CreERT2:Dnmt1 fl/fl:ZsGreen l/s/l mice (Dnmt1 ... Web033055 B6.Cg-Tg(Cdh5-cre)1Spe/J VEC-cre transgenic mice express Cre recombinase under the control of a Cdh5 promoter with greater efficiency than other similar lines. They may have applications related to the study of hematopoietic stem cell lineages derived from vascular endothelial cells.
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Web017968 B6;129-Tg(Cdh5-cre)1Spe/J These VEC-cre transgenic mice express Cre recombinase under the control of a Cdh5 promoter with greater efficiency than other … Please use this form to enter mouse-related technical questions, comments, … Updated features: Recombinase (cre) structure search enhancements, … WebOct 3, 2024 · Disclosed are methods and compositions for treating cardiovascular diseases including cardiomyopathy and heart failure. Particularly disclosed are methods and compositions that utilize or comprise inhibitors of hypoxia-inducible factor (HIF)-2α or agonists/inducers of HIF prolyl hydroxylase domain-2 (PHD2) signaling for treating … bambam tree
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WebSep 9, 2024 · Whereas Tg(Cdh5-cre/ERT2)1Rha is present in five copies 86, the independently generated Tg ... Thanos, A. et al. Evidence for baseline retinal pigment epithelium pathology in the Trp1-Cre mouse. WebJul 9, 2024 · Here, we describe the development of an autochthonous mouse model of angiosarcoma driven by loss of p53 in VE-cadherin-expressing endothelial cells. Using Cdh5-Cre to drive recombination in adult endothelial cells, mice developed angiosarcomas with 100% penetrance upon homozygous deletion of Trp53 with a median lifespan of 325 … WebMar 30, 2024 · Characterization of the Hrh2 flox/flox, cdh5−Cre mouse. The #69 ES cell clone was then selected for blastocyst microinjection to generate the founder generation Hrh2 floxneo mice (F0), and deletion of Neo in the F1 (Hrh2 flox/+) mice was accomplished by crossing F0 male mice with WT females. armidian karyatama tbk annual report